invitrogen 17101-015 胶原酶II型

描述：

II 型胶原酶是从溶组织梭菌制备，用于细胞和组织的解离。

II 型胶原酶可应用于如下组织制备细胞：

肝
骨
甲状腺
心脏
唾液腺

胶原酶是一种蛋白酶，它能够特异性的结合 Pro-X-Glyc-Pro序列中，中性氨基酸（X）和甘氨酸之间的肽键。该序列高频率的存在于胶原中。胶原酶是唯一的一种可以降解广泛存在于结缔组织中的具有三股螺旋的天然胶原纤维的蛋白酶。

Collagenase is a protease that cleaves the bond between a neutral amino acid (X) and glycine in the sequence Pro-X-Glyc-Pro, which is found with high frequency in collagen. Collagenase is unique among proteases in its ability to degrade the triple-helical native collagen fibrils commonly found in connective tissues such as skin, tendon, blood vessels, and bone. Collagenase disaggregation is suitable for the culture of human tumors, mouse kidney, human adult and fetal brain, and many other tissues including epithelium. Collagenase is relatively gentle, dissociates well at physiological temperature and pH, and requires no mechanical agitation or special equipment.

Gibco® Collagenase Type II is isolated from Clostridium histolyticum and packaged as a lyophilized, non-sterile powder for research use in cell or tissue dissociation and organ perfusions. Gibco® Collagenase Type II activity is guaranteed to be greater than 125 units/mg. Compared to other collagenase preparations, Gibco® Collagenase Type II has higher clostripain activity and is well-suited for the digestion of heart, bone, thyroid, cartilage, and liver tissues.

注意事项：

For Research Use Only. Not for use in diagnostic procedures.